İkinci Bir Şans: Geleceği İnşa Etmek | özgür dandin | TEDxKirmiziCizgiHighSchool

Quick Overview

Dr. Özgür Dandin presents his cutting-edge research on regenerative medicine, particularly focusing on xenotransplantation (using genetically modified pig organs for human transplant) and the potential of using amniotic fluid as a superior organ preservation solution, citing successful preclinical trials with pig livers that functioned after being preserved in this fluid.

Key Points: Dr. Dandin was born in Giresun's Görele district in 1978 and completed his medical education at Gülhane Military Medical Academy, later serving as Chief Physician at a NATO post. He pursued research in organ transplantation, xenotransplantation, regenerative medicine, and biomedical technologies, including work at the University of Tennessee and as the owner of Aeternos Sol, a biotech company. He highlights the historical human quest for immortality, citing Gilgamesh and Egyptian myths, and contrasts this with modern efforts like genetic engineering and regenerative medicine. A major focus is on using genetically modified pig organs for human transplants, referencing a 2022 study in 'Stem Cell Research and Therapy' that showed promise for chronic liver disease. His research involves developing organ perfusion systems and testing amniotic fluid as an organ preservation solution, showing that pig livers preserved in this fluid maintained function for up to 17 days. The speaker mentions preliminary positive results showing reduced cell death (apoptosis) in organs preserved with amniotic fluid compared to standard solutions. Future projects include developing portable organ perfusion devices (one receiving a 4 million TL TÜSEB grant) and advancing 'in vivo' organ regeneration.

Context: The presentation is delivered by Doç. Dr. Özgür Dandin at a TEDx event, focusing on his medical and scientific research aimed at overcoming organ shortage, primarily through xenotransplantation and advanced organ preservation techniques. Dandin frames his work within the historical human desire for longevity and immortality, transitioning from ancient myths to modern scientific solutions like regenerative medicine and bioengineering.